Cortizone-10 Cream

Generic Name: Hydrocortisone with Aloe (hye-droe-KOR-ti-sone/AL-oh)Brand Name: Cortizone-10

Cortizone-10 Cream is used for:

Treating inflammation and itching due to certain skin conditions. It may also be used for other conditions as determined by your doctor.

Cortizone-10 Cream is a topical adrenocortical steroid. It works by reducing skin inflammation (redness, swelling, itching, and irritation) in a way that is not clearly understood.

Do NOT use Cortizone-10 Cream if:

  • you are allergic to any ingredient in Cortizone-10 Cream

Contact your doctor or health care provider right away if any of these apply to you.

Before using Cortizone-10 Cream:

Some medical conditions may interact with Cortizone-10 Cream. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have any kind of skin infection, cuts, scrapes, or lessened blood flow to your skin
  • if you have had a recent vaccination; have measles, tuberculosis, chickenpox, or shingles; or have had a positive tuberculosis test
  • if you are taking prednisone or similar medicines

Some MEDICINES MAY INTERACT with Cortizone-10 Cream. Because little, if any, of Cortizone-10 Cream is absorbed into the blood, the risk of it interacting with another medicine is low.

Ask your health care provider if Cortizone-10 Cream may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Cortizone-10 Cream:

Use Cortizone-10 Cream as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Apply a small amount of medicine to the affected area. Gently rub the medicine in until it is evenly distributed. Wash your hands after applying Cortizone-10 Cream, unless your hands are part of the treated area.
  • If you are using Cortizone-10 Cream for external anal itching, do not put Cortizone-10 Cream into the rectum by using your fingers or any mechanical device or applicator. When practical, wash the affected area with mild soap and water, rinse thoroughly, and pat or blot dry with a toilet tissue or soft cloth before using Cortizone-10 Cream.
  • Do not bandage or cover the treated skin area unless directed by your doctor.
  • If you miss a dose of Cortizone-10 Cream, apply it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not apply 2 doses at once.

Ask your health care provider any questions you may have about how to use Cortizone-10 Cream.

Important safety information:

  • Cortizone-10 Cream is for external use only. Do not get Cortizone-10 Cream in your eyes. If contact is made with the eyes, flush them immediately with tap water.
  • Do not use Cortizone-10 Cream to treat diaper rash.
  • Do not use Cortizone-10 Cream to treat external female itching if you have a vaginal discharge.
  • Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
  • If your symptoms do not get better within 7 days, if they clear up and then come back, or if they get worse, check with your doctor.
  • Check with your doctor before having vaccinations while using Cortizone-10 Cream.
  • Cortizone-10 Cream has a corticosteroid in it. Before you start any new medicine, check the label to see if it has a corticosteroid in it too. If it does or if you are not sure, check with your doctor or pharmacist.
  • Corticosteroids may affect growth rate in CHILDREN and teenagers in some cases. They may need regular growth checks while they use Cortizone-10 Cream.
  • Cortizone-10 Cream should not be used in CHILDREN younger than 2 years old without first checking with your doctor; safety and effectiveness in these children have not been confirmed
  • Cortizone-10 Cream should not be used for external anal itch in CHILDREN younger than 12 years old without first checking with your doctor; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Cortizone-10 Cream while you are pregnant. It is not known if Cortizone-10 Cream is found in breast milk. If you are or will be breast-feeding while you use Cortizone-10 Cream, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Cortizone-10 Cream:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dryness; itching.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); acne-like rash; burning, cracking, irritation, or peeling not present before you began using Cortizone-10 Cream; excessive hair growth; inflamed hair follicles; inflammation around the mouth; muscle weakness; rectal bleeding; thinning, softening, or discoloration of the skin; unusual weight gain, especially in the face.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (, or emergency room immediately. Symptoms may include increased thirst or urination; muscle weakness; unusual weight gain, especially in the face.

Proper storage of Cortizone-10 Cream:

Store Cortizone-10 Cream at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not freeze. Do not store in the bathroom. Keep Cortizone-10 Cream out of the reach of children and away from pets.

General information:

  • If you have any questions about Cortizone-10 Cream, please talk with your doctor, pharmacist, or other health care provider.
  • Cortizone-10 Cream is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Cortizone-10 Cream. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

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