CRINONE is a vaginal gel that contains natural progesterone.
Progesterone is a hormone that is produced by the ovaries during the second half of the menstrual cycle.
It is an essential hormone for preparing the uterus (womb) for pregnancy and on-going support of pregnancy.
The lack of normal progesterone production by the ovaries in the second half of the menstrual cycle is called luteal phase defect. Women who have this defect may have difficulties in becoming pregnant and may have a higher risk of miscarriage.
CRINONE is used to supplement progesterone in women who have luteal phase defect. CRINONE is also used to supplement or replace your own natural progesterone in Assisted Reproductive Technology procedures (eg IVF).
Your doctor may have prescribed CRINONE for another purpose.
Ask your doctor if you have any questions why CRINONE has been prescribed for you.
This medicine is available only with a doctor's prescription.
CRINONE is not addictive.
Do not use CRINONE if:
Some of the symptoms of an allergic reaction may include:
Do not use CRINONE if you have, or have had any of the following conditions:
Do not use CRINONE if you are breastfeeding.
Do not use CRINONE after the expiry date printed on the label of the pre-filled applicator and the carton.
If you are taking this medicine after the expiry date has passed, it may not work.
Do not use CRINONE if the packaging is torn or shows signs of tampering.
Do not use CRINONE if the product appears to be discoloured, or the product does not look quite right.
If it has expired or is damaged, return it to your pharmacist or doctor for disposal.
If you are not sure whether you should start using CRINONE, talk to your doctor or pharmacist.
If you have not told your doctor about any of the above, tell them before you start using CRINONE.
CRINONE is not for use in children.
Do not use CRINONE to treat other complaints unless your doctor says it is safe.
Do not give this medicine to anyone else.
Tell your doctor or pharmacist if you have allergies to:
See your doctor for a check-up before you start to use CRINONE. The check-up should include a Pap smear, pelvic examination and breast examination.
You must tell your doctor or pharmacist if:
If in doubt, consult your doctor or pharmacist before using CRINONE.
Tell your doctor if you are taking any other medicines, including medicines you buy without a prescription from a pharmacy, supermarket or health food shop.
CRINONE should not be used at the same time as other vaginal preparations.
If you forget a dose of CRINONE, use it as soon as you remember, and then continue on the same schedule as before.
Do not use more than the recommended daily dose.
Immediately contact your doctor or the Poisons Information Centre (in Australia telephone 131 126, in New Zealand telephone 0800 764 766) if you are concerned that you have used too much Crinone.
Be sure to keep all your doctor's appointments so your progress can be checked.
Tell any other doctors or pharmacists you visit that you are using CRINONE.
If you are about to start taking any new medicines, tell the doctor or pharmacist that you are using CRINONE.
Do not give this medicine to anyone else; it may harm them even if the reasons for using it seem to be the same as yours.
Be careful driving or operating machinery until you know how CRINONE affects you.
Some people feel drowsy and sleepy when using CRINONE.
If you have any of these symptoms, do not drive, operate machinery or do anything else that could be dangerous.
Tell your doctor or pharmacist as soon as possible if you do not feel well while you are using CRINONE.
CRINONE helps most women with a lack of progesterone, but it may have unwanted side effects in a few people.
All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects.
Tell your doctor if you notice any of the following side effects when using CRINONE:
Other side effects may include vaginal spotting, vaginal irritation, mild application site reactions and hypersensitivity reactions manifesting as skin rash.
This is not a complete list of all possible side effects. Others may occur in some people and there may be some side effects not yet known.
Tell your doctor if you notice anything else that is making you feel unwell, even if it is not on this list.
Ask your doctor or pharmacist if you do not understand anything in this list.
Do not be alarmed by this list of possible side effects.
You may not experience any of them.
Ask your doctor or pharmacist to answer any questions you may have.
Keep this medicine where young children cannot reach it.
A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.
Keep CRINONE in a cool place where it stays below 25°C and is not exposed to extreme heat or cold.
Do not store it, or any other medicine, in a bathroom or near a sink.
Do not leave it in the car or on window sills.
Heat and dampness can destroy some medicines.
Each applicator must be used once only. Use a new applicator for each treatment.
If your doctor tells you to stop using CRINONE, or the gel has passed its expiry date, ask the pharmacist what to do with any left over drug.
CRINONE is a soft, white to off-white gel. It is supplied in an applicator with a twist-off top. The applicator contains a plastic ball. Each applicator is sealed in a wrapper and contains a single dose of CRINONE.
Each applicator contains 1.45 g of gel and delivers a constant dose of 1.125 g of CRINONE gel containing 90 mg (8% gel) of progesterone.
CRINONE is available in boxes containing 6, 15 or 18 applicators.
paraffin light liquid.