What CYKLOKAPRON is used for

CYKLOKAPRON is used to prevent excessive bleeding in patients with:

  • traumatic hyphaema (bleeding into the front part of the eye)
  • blood clotting disorders, who are having minor surgery
  • heavy periods
  • hereditary angioneurotic oedema (periodic swelling of the throat)

It may also be used to reduce bleeding and the need for transfusion of blood in patients undergoing heart surgery, total knee replacement and total hip replacement surgery.


CYKLOKAPRON contains tranexamic acid. Tranexamic acid is an antifibrinolytic that works by slowing the processes that cause bleeding.

Before taking CYKLOKAPRON

When you must not take it

Do not take CYKLOKAPRON if you have an allergy to CYKLOKAPRON or any of the ingredients listed at the end of this leaflet.

Do not take CYKLOKAPRON if you are being treated for a stroke.

Do not take CYKLOKAPRON if you are being treated for blood clots in your legs, lungs or anywhere else in your body.

Do not take CYKLOKAPRON if you have a problem with colour vision that developed after you were born.

Do not take CYKLOKAPRON after the expiry date (EXP) printed on the pack.

If you take this medicine after the expiry date has passed, it may not work as well.

Do not take CYKLOKAPRON if the packaging is torn or shows signs of tampering.

Do not take CYKLOKAPRON to treat any other complaint unless your doctor tells you to.

Before you start to take it

You must tell your doctor before you start to take CYKLOKAPRON if you have any of the following:

  • you, or someone in your family, has ever suffered from blood clots
  • severe bruising
  • kidney disease with or without blood in the urine
  • are pregnant or think you may be pregnant
  • are breastfeeding or plan to breastfeed
  • irregular periods and the reason is not known.

Convulsions, fits or seizures have been reported with CYKLOKAPRON treatment.

Tell your doctor if you have or have ever suffered from convulsion, fits or seizures before you start taking CYKLOKAPRON.

Tell your doctor if you have allergies to:

  • any other medicines
  • any other substances, such as foods, preservatives or dyes.

If you have not told your doctor about any of these things, tell him/her before you start taking CYKLOKAPRON.

Do not give this medicine to anyone else even if they have the same condition as you.

Taking other medicines

Tell your doctor about any other medicines you are taking including medicines that you buy without a prescription, in a pharmacy, supermarket or health food shop.

Some medicines may interfere with CYKLOKAPRON. These include:

  • other medicines used to prevent bleeding
  • medicines used to thin the blood

These medicines may affect the way CYKLOKAPRON works.


How to take it

Follow all directions given to you by your doctor or pharmacist carefully.

They may differ from the information contained in this leaflet.

Traumatic hyphaema (bleeding to the front part of the eye)

Take two or three tablets every 8 hours, for six to seven days. Swallow the tablets with water.

Heavy periods

Take two or three tablets four times a day for four days. Start taking the tablets when you first notice the bleeding. Take CYKLOKAPRON tablets for the first four days of your period. See your doctor for a check up after three months of treatment. If the bleeding is not reduced, talk to your doctor. Swallow the tablets with water.

Hereditary Angioneurotic Oedema (periodic swelling of the throat)

The usual dose is two or three tablets, 2 to 3 times a day. Your doctor will tell you how long to take the tablets. Swallow the tablets with water.

For those with a clotting disorder, having minor surgery

The usual dose is two or three tablets, 2 to 3 times a day. Your doctor will tell you how long to take the tablets. Swallow the tablets with water.

The directions your doctor gives you should be strictly followed.

If you do not understand the instructions in this leaflet, ask your doctor or pharmacist for help.

Cardiac Surgery and Total Knee or Total Hip Replacement Surgery

Your doctor will determine the dose that you will be given, based on your weight. The dose used in children undergoing heart surgery may be different to the dose used in adult heart surgery. The dose may vary depending on whether you suffer from diseases relating to the kidneys.

If you forget to take it

Take your CYKLOKAPRON tablet(s) as soon as you remember and then go back to taking it as you normally would.

If it is almost time for your next dose, skip the dose you have missed and take your next dose when you are meant to.

Do not try to make up for missed doses by taking more than one dose at a time because this may increase the chance of you getting an unwanted side effect.

If you have trouble remembering when to take your medicine, ask your pharmacist for some hints.

If you take too much (overdose)

Immediately telephone your doctor or Poisons Information Centre for advice (in Australia telephone 13 11 26, in New Zealand telephone 0800 POISON (0800 764 766) or go to Accident & Emergency at your nearest hospital if you think you or anyone else has taken too much CYKLOKAPRON, even if there are no signs of discomfort or poisoning.

You may need urgent medical attention.

Have CYKLOKAPRON or this leaflet available to give details if needed.

Keep telephone numbers for these places handy.

If you take too much CYKLOKAPRON you may have the following symptoms:

  • dizziness
  • headache
  • nausea
  • diarrhoea
  • low blood pressure
  • convulsions, fits or seizures.

While you are taking CYKLOKAPRON

Things you must do

Tell any other doctors, dentists and pharmacists who are treating you that you are taking CYKLOKAPRON.

If you start on any new medicine, tell your doctor, dentist or pharmacist that you are taking CYKLOKAPRON.

Side effects

Tell your pharmacist or doctor as soon as possible if you do not feel well while you are taking CYKLOKAPRON.

All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects.

Tell your doctor, nurse or pharmacist if you notice any of the following and they worry you:

  • nausea
  • vomiting
  • diarrhoea

These are the more common side effects of CYKLOKAPRON. Mostly these are mild and short-lived.

Following cardiac surgery, total knee replacement or total hip replacement surgery, tell your doctor or nurse immediately if you experience any of the following

  • irregular and often rapid heart beat
  • heart attack
  • slow or irregular heart beat
  • cardiogenic shock caused by very low blood pressure. The symptoms are dizziness and light headedness, rapid, weak pulse, white skin, sweating, restlessness, loss of consciousness, fainting, rapid, shallow breathing, cold clammy skin and weakness,
  • stroke. The symptoms of stroke are numbness or weakness of the arms or legs, headache, dizziness and confusion, visual disturbance, difficulty swallowing, slurred speech and loss of speech.
  • kidney problems where you pass little or no urine, drowsiness, nausea, vomiting and breathlessness
  • difficulty breathing
  • a condition called deep vein thrombosis (DVT). The symptoms of DVT are pain and swelling in the large veins, usually in your legs. DVT may lead to complications such as blood clots in your lungs
  • bowel infarction caused by a restriction of blood supply to the bowels. You may experience severe abdominal pains and may pass bloody stools.

These are serious side effects. You may need urgent medical attention.

Tell your doctor immediately or go to Accident and Emergency at your nearest hospital if you notice any of the following:

  • unexpected pain
  • unexpected swelling in your legs or arms
  • giddiness or dizziness
  • allergic skin reactions
  • changes in your eyesight
  • convulsions, fits or seizures
  • low blood pressure from rapid administration of CYKLOKAPRON Solution for Injection.

These may be serious side effects. You may need urgent medical attention.

These side effects are rare.

Other side effects not listed above may occur in some patients.

Tell your doctor if you notice any other side effects while taking CYKLOKAPRON.

Do not be alarmed by this list of possible side effects.

You may not experience any of them.

After taking CYKLOKAPRON


Keep your CYKLOKAPRON tablets in a cool, dry place where the temperature stays below 30°C.

Do not store CYKLOKAPRON tablets or any other medicine in the bathroom or near a sink.

Do not leave your tablets in the car on hot days or on a window sill.

Heat and dampness can destroy some medicines.


A locked cupboard at least one and a half metres above the ground is a good place to store medicines.

CYKLOKAPRON Solution for Injection will normally be stored in a hospital. The undiluted product should be stored in a cool, dry place where the temperature stays below 25°C. Do not freeze. Protect from light.

This product does not contain antimicrobial agents. It is for single use in one patient only.

If storage of the diluted solution is necessary, it should be stored at 2°C-8°C for a maximum of 24 hours. Any unused solution should be discarded.


If your doctor or pharmacist tells you to stop taking CYKLOKAPRON or the medicine has passed the expiry date, ask your pharmacist what to do with any medicine that is left over.

Remember: this medicine is for you. Never give it to someone else even if they have the same condition as you.

Product Description

What it looks like

CYKLOKAPRON tablets are white, capsule shaped tablets. The tablets are scored on one side and marked with 'CY' on the other.

CYKLOKAPRON Solution for Injection is a clear and colourless solution.


The active ingredient in CYKLOKAPRON is tranexamic acid.

Each CYKLOKAPRON tablet contains 500 mg of tranexamic acid.

The inactive ingredients are:

  • microcrystalline cellulose
  • hydroxypropylcellulose
  • talc
  • magnesium stearate
  • colloidal anhydrous silica
  • povidone
  • water.

Other ingredients that are in the tablet coating are:

  • Eudragit E100
  • titanium dioxide
  • macrogol 8000
  • vanillin.

CYKLOKAPRON tablets do not contain gluten, sucrose, tartrazine or other azo dyes.

CYKLOKAPRON ampoules each contains 100 mg/mL tranexamic acid.

The inactive ingredient is

  • Sterile Water for Injections.

Pack sizes

CYKLOKAPRON tablets are available in bottles of 100 tablets.

CYKLOKAPRON Solution for Injection is available in packs of

  • 5 x 5 mL and 10 x 5 mL ampoules each containing 500 mg tranexamic acid and 5 mL Water for Injections (not available in Australia).
  • 1 x 10 mL and 10 x 10 mL ampoules each containing 1000 mg tranexamic acid and 10 mL Water for Injections (not available in NZ).

If you want to know more

If you have any questions about your treatment with CYKLOKAPRON, ask your doctor or pharmacist.