Ketorolac Tromethamine Drops

Generic Name: Ketorolac Tromethamine (KEE-toe-ROLE-ak troe-METH-a-meen)Brand Name: Acuvail

Ketorolac Tromethamine Drops are used for:

Treating eye pain and swelling following cataract surgery. It may also be used for other conditions as determined by your doctor.

Ketorolac Tromethamine Drops are a nonsteroidal anti-inflammatory drug (NSAID). It works by blocking certain substances (prostaglandins) in the eye.

Do NOT use Ketorolac Tromethamine Drops if:

  • you are allergic to any ingredient in Ketorolac Tromethamine Drops
  • if you have had a severe allergic reaction (eg, severe rash, hives, breathing difficulties, dizziness) to aspirin, an NSAID (eg, ibuprofen, naproxen, celecoxib), or phenylacetic acid
  • you are in late pregnancy

Contact your doctor or health care provider right away if any of these apply to you.

Before using Ketorolac Tromethamine Drops:

Some medical conditions may interact with Ketorolac Tromethamine Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have asthma, diabetes, bleeding problems, or rheumatoid arthritis
  • if you have other eye problems (eg, dry eye syndrome, cornea problems, glaucoma or increased pressure in the eye), have had complicated eye surgery, or have had repeated eye surgeries within a short period of time
  • if you have a herpes infection in the eye

Some MEDICINES MAY INTERACT with Ketorolac Tromethamine Drops. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Anticoagulants (eg, warfarin), aspirin, corticosteroids (eg, prednisone), heparin, or NSAIDs (eg, ibuprofen) because the risk of side effects, such as bleeding, may be increased
  • Topical corticosteroids for the eye (eg, dexamethasone) because they may slow or delay the healing of the eye

This may not be a complete list of all interactions that may occur. Ask your health care provider if Ketorolac Tromethamine Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Ketorolac Tromethamine Drops:

Use Ketorolac Tromethamine Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with Ketorolac Tromethamine Drops. Talk to your pharmacist if you have questions about this information.
  • Ketorolac Tromethamine Drops are only for the eye. Do not get it in your nose or mouth.
  • To use Ketorolac Tromethamine Drops in the eye, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eyelid for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean, dry tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.
  • To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed.
  • Each vial of Ketorolac Tromethamine Drops are intended for single use only. Throw away any unused medicine in the vial immediately after you have used your dose.
  • If you are using other eye medicines, wait at least 5 minutes before applying them to the eye.
  • Do not wear contact lenses while you are using Ketorolac Tromethamine Drops. Take care of your contact lenses as directed by the manufacturer. Check with your doctor before you use them.
  • Do not use Ketorolac Tromethamine Drops if it is discolored or contains particles.
  • If you miss a dose of Ketorolac Tromethamine Drops and you are using it regularly, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Ketorolac Tromethamine Drops.

Important safety information:

  • Ketorolac Tromethamine Drops may cause blurred vision. This effect may be worse if you take it with alcohol or certain medicines. Use Ketorolac Tromethamine Drops with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do NOT use more than the recommended dose or use for longer than prescribed without checking with your doctor. Doing so may increase your risk for side effects, some of which may be serious.
  • Using Ketorolac Tromethamine Drops more than 24 hours before surgery or for more than 14 days after surgery may increase your risk of side effects, some of which may be serious.
  • If your symptoms do not get better within a few days or if they get worse, check with your doctor.
  • Tell your doctor if you have a tendency to bleed easily.
  • Contact your health care provider at once if you develop another eye condition (eg, trauma, eye surgery, infection) while taking Ketorolac Tromethamine Drops. It may be necessary to stop using Ketorolac Tromethamine Drops.
  • Ketorolac Tromethamine Drops may cause harm if it is swallowed. If you may have taken it by mouth, contact your poison control center or emergency room right away.
  • Ketorolac Tromethamine Drops should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: Avoid using Ketorolac Tromethamine Drops late in pregnancy. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Ketorolac Tromethamine Drops while you are pregnant. It is not known if Ketorolac Tromethamine Drops are found in breast milk after topical use. If you are or will be breast-feeding while you use Ketorolac Tromethamine Drops, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Ketorolac Tromethamine Drops:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Blurred vision; headache; increased tear production; swelling of the cornea and iris; temporary burning, irritation, pain, redness, stinging, or swelling of the eye.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); continuous pain, burning, irritation, stinging, redness, or swelling around the eyes; infection in the eye; unusual bleeding; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (, or emergency room immediately.

Proper storage of Ketorolac Tromethamine Drops:

Store Ketorolac Tromethamine Drops between 59 and 86 degrees F (15 and 30 degrees C). Store the vials in the pouch provided with pouch ends folded closed. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Ketorolac Tromethamine Drops out of the reach of children and away from pets.

General information:

  • If you have any questions about Ketorolac Tromethamine Drops, please talk with your doctor, pharmacist, or other health care provider.
  • Ketorolac Tromethamine Drops are to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Ketorolac Tromethamine Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

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